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Article

Inhibition of mitochondrial division through covalent modification of Drp1 protein by 15 deoxy-Delta(12,14)-prostaglandin J2.

Biochemical and biophysical research communications - 23 Apr 2010

Mishra Nandita, Kar Rekha, Singha Prajjal K, Venkatachalam Manjeri A, McEwen Donald G, Saikumar Pothana

Abstract excerpt

Arachidonic acid derived endogenous electrophile 15d-PGJ2 has gained much attention in recent years due to its potent anti-proliferative and anti-inflammatory actions mediated through thiol modification of cysteine residues in its target proteins. Here, we show that 15d-PGJ2 at 1 microM concentra...

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Identifiers

PMID: 20307494
DOI: 10.1016/j.bbrc.2010.03.093
PMCID: PMC2859997

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20307494-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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