Article

Anastrozole mediated modulation of mitochondrial activity by inhibition of mitochondrial permeability transition pore opening: An initial perspective

2019-08-05

Abstract excerpt

<h4>Background</h4> Mitochondrial permeability transmembrane pore [mPTP] plays a vital role in alteration of the structure and function of mitochondria. Cyclophillin D is a mitochondrial protein that regulates mPTP function and a known drug target for therapeutic studies involving mitochondria. While aromatase inhibitor’s role on mPTP has been previously studied, the role of anastrazole on mPTP is not completely...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 391fcbae-6baf-58a3-9d4a-6b116e2f8ff9
DOI: 10.1101/724872

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 8 closest

Anastrozole mediated modulation of mitochondrial activity by inhibition of mitochondrial permeability transition pore opening: An initial perspectiveDOI 10.1101/724872Read

Redox characterization of human cyclophilin D: identification of a new mammalian mitochondrial redox sensor?Semantic proximity Read

Evaluating the efficacy of vatiquinone in preclinical models of mitochondrial diseaseSemantic proximity Read

Involvement of cyclophilin D in mitochondrial permeability transition induction in intact cells.Semantic proximity Read

Mechanism of Action of Ropeginterferon Alfa-2b in Polycythemia Vera TreatmentSemantic proximity Read

Mitochondrial dysfunction and potential anticancer therapySemantic proximity Read

New insights into mitochondrial quality control in anthracycline-induced cardiotoxicity: molecular mechanisms, therapeutic targets, and natural productsSemantic proximity Read

Recent topics: the diagnosis, molecular genesis, and treatment of mitochondrial diseasesSemantic proximity Read

Classification of mitocans, anti-cancer drugs acting on mitochondria.Semantic proximity Read