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Evaluating Lynch syndrome in very early onset colorectal cancer probands without apparent polyposis.

Familial cancer - 1 Jun 2010

Jasperson Kory W, Vu Thuy M, Schwab Angela L, Neklason Deborah W, Rodriguez-Bigas Miguel A, Burt Randall W, Weitzel Jeffrey N

Abstract excerpt

To characterize the frequency of germline mutations associated with Lynch syndrome and review the potential expanded differential diagnoses in very early onset colorectal cancer (CRC) cases without apparent polyposis. Retrospectively reviewed medical records of 96 probands with CRC diagnosed prior to age 36 from three cancer centers. Determined the frequency of germline mutations in probands meeting different...

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Identifiers

PMID: 19731080
DOI: 10.1007/s10689-009-9290-4
PMCID: PMC3620042

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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