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Article

Early-onset colorectal cancer patients without family history are “at very low risk” for lynch syndrome

2 Jan 2014

Abstract excerpt

INTRODUCTION: Several studies evaluated the prevalence of Lynch Syndrome (LS) in young onset colorectal cancer (CRC) patients and the results were extremely variable (5%-20%). Immunohistochemistry (IHC) for MMR proteins and/or MSI analysis are screening tests that are done, either by themselves or in conjunction, on colon cancer tissue to identify individuals at risk for LS. The primary aim of our study was to...

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PMID: 24383517
DOI: 10.1186/1756-9966-33-1

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