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Article

Lynch syndrome and Lynch syndrome mimics: The growing complex landscape of hereditary colon cancer.

World journal of gastroenterology - 21 Aug 2015

Carethers John M, Stoffel Elena M

Abstract excerpt

Hereditary non-polyposis colorectal cancer (HNPCC) was previously synonymous with Lynch syndrome; however, identification of the role of germline mutations in the DNA mismatch repair (MMR) genes has made it possible to differentiate Lynch syndrome from other conditions associated with familial colorectal cancer (CRC). Broadly, HNPCC may be dichotomized into conditions that demonstrate defective DNA MMR and...

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Source

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Identifiers

PMID: 26309352
DOI: 10.3748/wjg.v21.i31.9253
PMCID: PMC4541378

Genes

MLH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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