Article
Increased hepatic myeloperoxidase activity in obese subjects with nonalcoholic steatohepatitis.
The American journal of pathology - 1 Oct 2009
Rensen Sander S, Slaats Yanti, Nijhuis Jeroen, Jans Anneke, Bieghs Veerle, Driessen Ann, Malle Ernst, Greve Jan Willem, Buurman Wim A
Abstract excerpt
Inflammation and oxidative stress are considered critical factors in the progression of nonalcoholic fatty liver disease. Myeloperoxidase (MPO) is an important neutrophil enzyme that can generate aggressive oxidants; therefore, we studied the association between MPO and nonalcoholic fatty liver disease. The distribution of inflammatory cells containing MPO in liver biopsies of 40 severely obese subjects with...
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