Article
Correlations of autoimmunity with H-2 and T cell receptor beta chain genotypes in (NZB X NZW) F2 mice.
European journal of immunology - 1 May 1990
Noonan D J, McConahey P J, Cardenas G J
Abstract excerpt
Accelerated autoimmunity as expressed by the classical autoimmune strain mouse (NZB x NZW)F1 is thought to be the result of major histocompatibility complex (MHC)-associated NZW genes acting on a genetic predisposition for autoimmunity as expressed by the NZB mouse. To evaluate more accurately bo...
Topics
- Animals
- Antibodies, Antinuclear
- Antibodies, Viral
- Autoimmunity
- Chromosome Deletion
- Crosses, Genetic
- DNA
- DNA, Single-Stranded
- Female
- Genotype
- H-2 Antigens
- Haplotypes
- Homozygote
- Male
- Mice
- Polymorphism, Restriction Fragment Length
- Receptors, Antigen, T-Cell
- Receptors, Antigen, T-Cell, alpha-beta