Article
CD8+ cells and natural cytotoxic activity among spleen, blood, and heart lymphocytes during the acute phase of Trypanosoma cruzi infection in rats.
Infection and immunity - 1 Mar 1992
Sato M N, Yamashiro-Kanashiro E H, Tanji M M, Kaneno R, Higuchi M L, Duarte A J
Abstract excerpt
The infection developed by Wistar Furth rats inoculated with the Y strain of Trypanosoma cruzi was the experimental model used in our study. The results showed that this infection altered considerably the CD4/CD8 lymphocyte subset ratio and the natural cytotoxic activity of mononuclear cells in the spleen, blood, and myocardial tissue. Concomitantly, an expansion of the number of cells expressing major...
Topics
- Acute Disease
- Animals
- CD8 Antigens
- Chagas Disease
- Female
- Histocompatibility Antigens Class II
- Killer Cells, Natural
- Lymphocyte Subsets
- Male
- Myocardium
- Phenotype