Further characterization of protective Trypanosoma cruzi-specific CD4+ T-cell clones: T helper type 1-like phenotype and reactivity with shed trypomastigote antigens.

doi:10.1128/iai.61.8.3250-3258.1993

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Article

Further characterization of protective Trypanosoma cruzi-specific CD4+ T-cell clones: T helper type 1-like phenotype and reactivity with shed trypomastigote antigens.

Infection and immunity - 1 Aug 1993

Nickell S P, Keane M, So M

Abstract excerpt

We previously reported the isolation from immune mice of a panel of murine clonal T-cell lines which specifically recognize antigens expressed by the trypomastigote stage of the protozoan parasite Trypanosoma cruzi, the causative agent of human Chagas' disease. Our analysis indicated that distinc...

Topics

Animals
Antigens, Protozoan
Clone Cells
Female
Immunoblotting
Lymphocyte Activation
Lymphokines
Mice
Mice, Inbred C57BL
Phenotype
T-Lymphocytes, Helper-Inducer
Trypanosoma cruzi

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