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Cytokine mRNA Profile of Peripheral Blood Mononuclear Cells Isolated from Individuals with <i>Trypanosoma cruzi</i> Chronic Infection

1 Jan 1997

Abstract excerpt

Characterization of immunologic activities during chronic infection with Trypanosoma cruzi is critical for understanding the dynamics of human Chagas' disease. Since cytokine production is mainly regulated by transcription and mRNA stability, quantitative RT-PCR analysis gives an accurate picture of the influences of disease on cytokine profile. Using RT-PCR, the authors analysed the levels of message expression...

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Identifiers

PMID: 9010503
DOI: 10.1046/j.1365-3083.1997.d01-362.x

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