Article
Phenotype and cytokine profile of Schistosoma mansoni specific T cell lines and clones derived from schistosomiasis patients with distinct clinical forms.
Clinical immunology (Orlando, Fla.) - 1 Jun 1999
Contigli C, Silva-Teixeira D N, Del Prete G, D'Elios M M, De Carli M, Manghetti M, Amedei A, Almerigogna F, Lambertucci J R, Goes A M
Abstract excerpt
It is essential to distinguish the role of T lymphocytes on the physiopathology associated to more severe forms of schistosomiasis and on the immunomodulation that evolves in the majority of infected people. In this study, we generated Schistosoma mansoni-specific T cell lines and clones from patients with the acute and chronic (intestinal and hepatosplenic forms) phases of disease, from former ones, and from...
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