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Article

Change in the Th1/Th2 Phenotype of Memory T‐Cell Clones from Rheumatoid Arthritis Synovium

1 Jul 1999

Abstract excerpt

The stability of established memory T helper (Th)1/Th2 cells in chronic inflammatory diseases is not clear, and a shift of the cytokine balance could control chronic inflammation. In order to study the regulation of the Th phenotype of memory T cells, polyclonal T-cell lines and clones with a Th1, Th0 or Th2 phenotype were developed from rheumatoid synovial tissue. Th1 [interleukin (IL)-12 + anti-IL-4] and Th2...

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Identifiers

PMID: 10404044
DOI: 10.1046/j.1365-3083.1999.00581.x

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