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Article

Comparative analysis of thymidylate synthase at the protein, mRNA, and DNA levels as prognostic markers in colorectal adenocarcinoma.

Journal of surgical oncology - 1 Dec 2009

Ren Dan-Ni, Kim Ik-Yong, Koh Sang Baek, Chang Sei Jin, Eom Minseob, Yi Sang Yeop, Seong Seung Hoon, Kim Mi-Dong, Bronner Mary P, Cho Mee-Yon

Abstract excerpt

BACKGROUND AND OBJECTIVES: To determine the best routinely available molecular methodology for assessing thymidylate synthase (TS) as a prognostic marker in colorectal adenocarcinoma, TS was examined at the protein, mRNA, and DNA levels. Direct comparison of these routinely available assays has not been systematically studied across a large colon cancer patient cohort with long-term follow-up. METHODS: We studied...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19722231
DOI: 10.1002/jso.21383

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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