Article
Characterization of V beta-bearing cells in athymic (nu/nu) mice suggests an extrathymic pathway for T cell differentiation.
European journal of immunology - 1 Apr 1990
Rocha B
Abstract excerpt
In the present article, the expression of the T cell receptor (TcR) beta chain and other T cell molecules was evaluated in surface immunoglobulin-negative spleen cell populations of young and old BALB/c and C57BL/6 nude mice, using a panel of monoclonal antibodies. The results obtained show that...
Topics
- Age Factors
- Animals
- Antigens, Differentiation, T-Lymphocyte
- Antigens, Surface
- CD3 Complex
- CD4 Antigens
- CD8 Antigens
- Cell Differentiation
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Mice, Nude
- Phenotype
- Receptors, Antigen, B-Cell
- Receptors, Antigen, T-Cell
- Receptors, Antigen, T-Cell, alpha-beta
- T-Lymphocytes
- Thy-1 Antigens