Article
Demonstration of a CD3+ lymphocyte subset in the epidermis of athymic nude mice. Evidence for T cell receptor diversity.
Journal of immunology (Baltimore, Md. : 1950) - 15 Jul 1992
Payer E, Strohal R, Kutil R, Elbe A, Stingl G
Abstract excerpt
The existence of CD3/TCR-bearing lymphocytes in athymic and thymectomized chimeric mice implies that T cell maturation can occur in the absence of a thymus. Considering the possibility that the epidermis may be one of the organs providing T cell educating stimuli, we attempted to characterize the...
Topics
- Age Factors
- Animals
- Antigens, Differentiation, T-Lymphocyte
- Antigens, Surface
- Base Sequence
- CD3 Complex
- Cell Line
- Epidermis
- Membrane Glycoproteins
- Mice
- Mice, Inbred Strains
- Mice, Nude
- Molecular Sequence Data
- Phenotype
- RNA, Messenger
- Receptors, Antigen, T-Cell
- T-Lymphocyte Subsets
- Thy-1 Antigens