Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SRC-3 Is Required for Prostate Cancer Cell Proliferation and Survival

1 Sept 2005

Abstract excerpt

Prostate cancer is the most common cancer in men in America. Currently, steroid receptor coactivators have been proposed to mediate the development and progression of prostate cancer, at times in a steroid-independent manner. Steroid receptor coactivator-3 (SRC-3, p/CIP, AIB1, ACTR, RAC3, and TRAM-1) is a member of the p160 family of coactivators for nuclear hormone receptors including the androgen receptor....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Estrogen and related hormone effects
Share to Prostate Cancer Treatment and Research
Share to RNA Research and Splicing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16140970
DOI: 10.1158/0008-5472.can-04-4076

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SRC-3 Is Required for Prostate Cancer Cell Proliferation and SurvivalPMID 16140970Read ↗

SRC-3 Has a Role in Cancer Other Than as a Nuclear Receptor CoactivatorSemantic proximity Read ↗

Steroid receptor coactivator-3 as a potential molecular target for cancer therapySemantic proximity Read ↗

The role of steroid receptor coactivator-3 (SRC-3) in human malignant disease.Semantic proximity Read ↗

Long non‐coding RNA PRRT3‐AS1 silencing inhibits prostate cancer cell proliferation and promotes apoptosis and autophagySemantic proximity Read ↗

Suppressor of Cytokine Signaling-3 Antagonizes cAMP Effects on Proliferation and Apoptosis and Is Expressed in Human Prostate CancerSemantic proximity Read ↗

Steroid‐induced androgen receptor–oestradiol receptor β–Src complex triggers prostate cancer cell proliferationSemantic proximity Read ↗

Critical Roles of SRC-3 in Development and Progression of Breast Cancer, Render it a Prospective Clinical TargetSemantic proximity Read ↗

ACTR/AIB1/SRC-3 and androgen receptor control prostate cancer cell proliferation and tumor growth through direct control of cell cycle genesSemantic proximity Read ↗

Down-Regulation of Signal Transducer and Activator of Transcription 3 Expression Using Vector-Based Small Interfering RNAs Suppresses Growth of Human Prostate Tumor <i>In vivo</i>Semantic proximity Read ↗

Inhibition of STAT3 signaling targets both tumor-initiating and differentiated cell populations in prostate cancerSemantic proximity Read ↗

Androgen-induced proliferative quiescence in prostate cancer cells: The role of AS3 as its mediatorSemantic proximity Read ↗

Cell-autonomous GP130 activation suppresses prostate cancer development via STAT3/ARF/p53-driven senescence and confers an immune-active tumor microenvironmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.