Article
Influence of mannose-binding lectin gene polymorphisms on the invasiveness of cytomegalovirus disease after solid organ transplantation.
Transplantation proceedings - 1 Jan 2000
Cervera C, Lozano F, Linares L, Antón A, Balderramo D, Suárez B, Pascal M, Sanclemente G, Cofán F, Ricart M J, Navasa M, Roig E, Marcos M A, Pumarola T, Moreno A
Abstract excerpt
BACKGROUND: Mannose-binding lectin (MBL) is a component of the innate immune system that binds the surface of pathogens, activating the complement pathway and acting as opsonin. Certain single-nucleotide polymorphisms of MBL2 are associated with a decrease in the circulating levels of MBL. Our aim was to evaluate the influence of MBL2 polymorphisms in the invasiveness of Cytomegalovirus (CMV) disease after solid...
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