Article
Sclera-related gene polymorphisms in high myopia.
Molecular vision - 20 Aug 2009
Lin Hui-Ju, Wan Lei, Tsai Yuhsin, Liu Su-Ching, Chen Wen-Chi, Tsai Shih-Wei, Tsai Fuu-Jen
Abstract excerpt
PURPOSE: Transforming growth factor-beta2 (TGF-beta2), basic fibroblast growth factor (bFGF), and fibromodulin (FMOD) are important extracellular matrix components of the sclera and have been shown to be associated with the development of high myopia. Our aim was to examine the association between myopia and the polymorphisms within TGF-beta2, bFGF, and FMOD. METHODS: The study group comprised of patients (n=195;...
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