Article
The TGFbeta1 gene codon 10 polymorphism contributes to the genetic predisposition to high myopia.
Molecular vision - 21 Jun 2006
Lin Hui-Ju, Wan Lei, Tsai Yuhsin, Tsai Yi-Yu, Fan Seng-Sheen, Tsai Chang-Hai, Tsai Fuu-Jen
Abstract excerpt
PURPOSE: Transforming growth factor-beta (TGFbeta), a multifunctional growth factor that plays a key role in the remodeling of scleral tissue, may be involved in the predisposition and pathophysiology of high myopia. Our aim was to examine the association between myopia and the polymorphisms within codon 10 of the TGFbeta1 gene. METHODS: This was a case control study. The study group contained participants who...
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