Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The association between lumican gene polymorphisms and high myopia.

Eye (London, England) - 1 Jun 2010

Lin H-J, Wan L, Tsai Y, Chen W-C, Tsai S-W, Tsai F-J

Abstract excerpt

PURPOSES: Lumican (LUM) is one of the major extracellular matrix components of the sclera. Increasing evidence suggests that changes in the structure and composition of the sclera are major factors in regulating scleral integrity and axial elongation of the eye, as in myopia. PATIENTS AND METHODS: Patients (n=182; age range, 17-24 years) were with a myopic spherical equivalent (SE)>6.5 diopters (D) and the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Chondroitin Sulfate Proteoglycans
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Haplotypes

Share to Myopia

Share to Polymorphism, Single Nucleotide

Share to Sequence Analysis, DNA

Share to Young Adult

Source

Identifiers

PMID: 20010793
DOI: 10.1038/eye.2009.254

Genes

LUM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The association between lumican gene polymorphisms and high myopia.PMID 20010793Read ↗

Association of the lumican gene functional 3'-UTR polymorphism with high myopia.Semantic proximity Read ↗

Meta-analysis of the association between lumican gene polymorphisms and susceptibility to high Myopia.Semantic proximity Read ↗

Absence of an association between lumican promoter variants and high myopia in the Korean population.Semantic proximity Read ↗

Association between a lumican promoter polymorphism and high myopia in the Chinese population: a meta-analysis of case-control studies.Semantic proximity Read ↗

Lack of association between LUM rs3759223 polymorphism and high myopia.Semantic proximity Read ↗

The association of haplotype at the lumican gene with high myopia susceptibility in Taiwanese patients.Semantic proximity Read ↗

Association of Lumican gene polymorphism with high myopia: a meta-analysis.Semantic proximity Read ↗

The association of single nucleotide polymorphisms in the 5'-regulatory region of the lumican gene with susceptibility to high myopia in Taiwan.Semantic proximity Read ↗

Ten SNPs of PAX6, Lumican, and MYOC genes are not associated with high myopia in Han Chinese.Semantic proximity Read ↗

Sclera-related gene polymorphisms in high myopia.Semantic proximity Read ↗

Novel mutations in the small leucine-rich repeat protein/proteoglycan (SLRP) genes in high myopiaSemantic proximity Read ↗

[Regulation of bFGF and TGF-β2 in human scleral fibroblasts by the lumican gene mutation associated with myopia].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.