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Article

Glyoxalase I gene deletion mutants of Leishmania donovani exhibit reduced methylglyoxal detoxification.

PloS one - 27 Aug 2009

Chauhan Swati C, Madhubala Rentala

Abstract excerpt

BACKGROUND: Glyoxalase I is a metalloenzyme of the glyoxalase pathway that plays a central role in eliminating the toxic metabolite methyglyoxal. The protozoan parasite Leishmania donovani possesses a unique trypanothione dependent glyoxalase system. PRINCIPAL FINDINGS: Analysis of the L. donovan...

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Identifiers

PMID: 19710909
DOI: 10.1371/journal.pone.0006805
PMCID: PMC2728510

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19710909-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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