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Article

The overexpression of genes of thiol metabolism contribute to drug resistance in clinical isolates of visceral leishmaniasis (kala azar) in India.

Parasites & vectors - 17 Dec 2014

Singh Neeloo, Chatterjee Mitali, Sundar Shyam

Abstract excerpt

BACKGROUND: Visceral leishmaniasis (VL), also called Kala Azar (KA) or black fever in India, claims around 20,000 lives every year. Chemotherapy remains one of the most important tools in the control of VL. Current chemotherapy for Kala Azar in India relies on a rather limited arsenal of drugs including sodium antimony gluconate and amphotericin B in addition to the very expensive drug miltefosine. Pentavalent...

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Identifiers

PMID: 25515494
DOI: 10.1186/s13071-014-0596-1
PMCID: PMC4280036

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