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Article

A gammaherpesvirus ubiquitin-specific protease is involved in the establishment of murine gammaherpesvirus 68 infection.

Journal of virology - 1 Oct 2009

Gredmark-Russ Sara, Isaacson Marisa K, Kattenhorn Lisa, Cheung Evelyn J, Watson Nicki, Ploegh Hidde L

Abstract excerpt

Murine gammaherpesvirus 68 (MHV-68) contains a ubiquitin (Ub)-specific cysteine protease (USP) domain embedded within the large tegument protein ORF64, as do all other herpesviruses. The biological role of this protease is still unclear, but for the alphaherpesvirus Marek's disease virus, its USP is involved in T-cell lymphoma formation. We here study the role of the MHV-68 USP, encoded by ORF64. By constructing...

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Identifiers

PMID: 19706716
DOI: 10.1128/JVI.01017-09
PMCID: PMC2753118

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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