Article
Murine gammaherpesvirus 68 open reading frame 75c tegument protein induces the degradation of PML and is essential for production of infectious virus.
Journal of virology - 1 Aug 2008
Ling Paul D, Tan Jie, Sewatanon Jaturong, Peng RongSheng
Abstract excerpt
Promyelocytic Leukemia nuclear body (PML NB) proteins mediate an intrinsic cellular host defense response against virus infections. Herpesviruses express proteins that modulate PML or PML-associated proteins by a variety of strategies, including degradation of PML or relocalization of PML NB prot...
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