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Conquering the Host: Determinants of Pathogenesis Learned from Murine Gammaherpesvirus 68

29 Sept 2021

Abstract excerpt

Gammaherpesviruses are an important class of oncogenic pathogens that are exquisitely evolved to their respective hosts. As such, the human gammaherpesviruses Epstein-Barr virus (EBV) and Kaposi sarcoma herpesvirus (KSHV) do not naturally infect nonhuman primates or rodents. There is a clear need to fully explore mechanisms of gammaherpesvirus pathogenesis, host control, and immune evasion in the host. A...

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PMID: 34586873
DOI: 10.1146/annurev-virology-011921-082615

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