Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comparison of FISH, PCR, and immunohistochemistry in assessing EGFR status in lung adenocarcinoma and correlation with clinicopathologic features.

Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Sept 2009

El-Zammar Ola A, Zhang Shengle, Katzenstein Anna-Luise A

Abstract excerpt

The purpose of this study is to investigate the relationship between mutation status, copy number, and protein expression of epidermal growth factor receptor (EGFR) in lung adenocarcinoma, and to correlate the genetic status and clinicopathologic features. Forty-nine adenocarcinomas were tested by polymerase chain reaction (PCR) for EGFR gene mutations, by fluorescence in situ hybridization (FISH) for increased...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ErbB Receptors

Share to Gene Dosage

Share to Gene Expression

Share to Immunohistochemistry

Share to In Situ Hybridization, Fluorescence

Share to Lung Neoplasms

Source

Identifiers

PMID: 19704257
DOI: 10.1097/PDM.0b013e3181857ea9

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comparison of FISH, PCR, and immunohistochemistry in assessing EGFR status in lung adenocarcinoma and correlation with clinicopathologic features.PMID 19704257Read ↗

Usefulness of tissue microarrays for assessment of protein expression, gene copy number and mutational status of EGFR in lung adenocarcinoma.Semantic proximity Read ↗

Relationship between EGFR expression, copy number and mutation in lung adenocarcinomas.Semantic proximity Read ↗

Evaluation of EGFR abnormalities in patients with pulmonary adenocarcinoma: the need to test neoplasms with more than one method.Semantic proximity Read ↗

Epidermal growth factor receptor gene amplification in surgical resected Japanese lung cancer.Semantic proximity Read ↗

Epidermal growth factor receptor (EGFR) high gene copy number and activating mutations in lung adenocarcinomas are not consistently accompanied by positivity for EGFR protein by standard immunohistochemistry.Semantic proximity Read ↗

Relationship between epidermal growth factor receptor gene mutation and copy number in Chinese patients with non-small cell lung cancer.Semantic proximity Read ↗

[Epidermal growth factor receptor gene mutations, amplification and clinicopathologic correlation in patients with lung cancer].Semantic proximity Read ↗

HER2 status in lung adenocarcinoma: a comparison of immunohistochemistry, fluorescence in situ hybridization (FISH), dual-ISH, and gene mutations.Semantic proximity Read ↗

Epidermal growth factor receptor gene copy number changes in lung cancer.Semantic proximity Read ↗

Significance of EGFR Protein Expression and Gene Amplification in Non–Small Cell Lung CarcinomaSemantic proximity Read ↗

Correlation of EGFR expression, gene copy number and clinicopathological status in NSCLCSemantic proximity Read ↗

Epidermal Growth Factor Receptor in Non–Small-Cell Lung Carcinomas: Correlation Between Gene Copy Number and Protein Expression and Impact on PrognosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.