Article
Epidermal growth factor receptor gene amplification in surgical resected Japanese lung cancer.
Lung cancer (Amsterdam, Netherlands) - 1 Jun 2009
Sasaki Hidefumi, Shimizu Shigeki, Okuda Katsuhiro, Kawano Osamu, Yukiue Haruhiro, Yano Motoki, Fujii Yoshitaka
Abstract excerpt
To evaluate the epidermal growth factor receptor (EGFR) protein expression and increased copy number as predictors of clinical outcome in patients with non-small-cell lung cancer (NSCLC), we have performed fluorescence in situ hybridization (FISH) and immunohistochemistry (IHC). We investigated the EGFR increased copy number and EGFR protein expression statuses in 109 surgically treated NSCLC cases. The presence...
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