Article
Epidermal growth factor receptor gene copy number changes in lung cancer.
Folia medica - 1 Jan 2000
Cherneva Radostina V, Georgiev Ognyan B, Petrov Danail B, Dimova Ivanka I, Toncheva Draga I
Abstract excerpt
OBJECTIVE: The objective of this study was to assess the implication of copy number changes of epidermal growth factor receptor (EGFR) in lung cancer pathogenesis. MATERIALS AND METHODS: We used the highly reliable method of FISH, applied on tissue microarray (TMA), containing 306 lung tumors of different histological types, grades and tumor stage, in order to analyze the correlations between gene copy number...
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