Article
Usefulness of tissue microarrays for assessment of protein expression, gene copy number and mutational status of EGFR in lung adenocarcinoma.
Virchows Archiv : an international journal of pathology - 1 Oct 2010
Ilie Marius I, Hofman Véronique, Bonnetaud Christelle, Havet Katia, Lespinet-Fabre Virginie, Coëlle Céline, Gavric-Tanga Virginie, Vénissac Nicolas, Mouroux Jerôme, Hofman Paul
Abstract excerpt
Specific inhibitors targeting the epidermal growth factor receptor (EGFR) can increase survival rates in certain lung adenocarcinoma patients with mutations in the EGFR gene. Although such EGFR-targeted therapies have been approved for use, there is no general consensus among surgical pathologists on how the EGFR status should be tested in lung adenocarcinoma tissues and whether the results of...
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