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Article

Evaluation of EGFR abnormalities in patients with pulmonary adenocarcinoma: the need to test neoplasms with more than one method.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jan 2009

Gupta Ruta, Dastane Aditi M, Forozan Farahnaz, Riley-Portuguez Amin, Chung Fai, Lopategui Jean, Marchevsky Alberto M

Abstract excerpt

Patients with advanced pulmonary adenocarcinoma exhibiting overexpression or mutation of epidermal growth factor receptor tend to respond better to targeted therapy with tyrosine kinase inhibitors such as gefitinib and erlotinib. There is no consensus regarding how these neoplasms should be routinely tested for epidermal growth factor receptor (EGFR) and whether the results of immunohistochemistry (IHC), mutation...

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Share to Adenocarcinoma
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ErbB Receptors

Share to Gene Amplification

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Share to In Situ Hybridization, Fluorescence

Share to Lung Neoplasms

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Source

Identifiers

PMID: 18997733
DOI: 10.1038/modpathol.2008.182

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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