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Article

HER2 status in lung adenocarcinoma: a comparison of immunohistochemistry, fluorescence in situ hybridization (FISH), dual-ISH, and gene mutations.

Lung cancer (Amsterdam, Netherlands) - 1 Sept 2014

Yoshizawa Akihiko, Sumiyoshi Shinji, Sonobe Makoto, Kobayashi Masashi, Uehara Takeshi, Fujimoto Masakazu, Tsuruyama Tatsuaki, Date Hiroshi, Haga Hironori

Abstract excerpt

OBJECTIVES: While novel anti-human epidermal growth factor receptor 2 (HER2) agents have recently been developed, no definite criteria have been proposed as indications for the use of these agents in patients with lung cancer. Here, we tested HER2 alterations by using four methods and explored the concordance of these methods to improve our understanding of the accuracy of HER2 testing methods. MATERIALS AND...

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Source

Identifiers

PMID: 25047676
DOI: 10.1016/j.lungcan.2014.06.007

Genes

EGFR
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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