Article
Relationship between EGFR expression, copy number and mutation in lung adenocarcinomas.
BMC cancer - 19 Jul 2010
Liang Zhiyong, Zhang Jing, Zeng Xuan, Gao Jie, Wu Shafei, Liu Tonghua
Abstract excerpt
BACKGROUND: This study was designed to investigate EGFR protein expression, EGFR copy number and EGFR mutations in lung adenocarcinomas, to explore the relationship of the three markers. METHODS: EGFR status was analyzed in surgically resected lung adenocarcinoma samples from 133 Chinese patients by three methods: protein expression (n=133) by standardized immunohistochemistry (IHC), gene copy number (n=133) by...
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