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Article

Association of catechol-O-methyltransferase (COMT) polymorphism and academic achievement in a Chinese cohort.

Brain and cognition - 1 Dec 2009

Yeh Ting-Kuang, Chang Chun-Yen, Hu Chung-Yi, Yeh Ting-Chi, Lin Ming-Yeh

Abstract excerpt

Catechol-O-methyltransferase (COMT) is a methylation enzyme that catalyzes the degradation pathway and inactivation of dopamine. It is accepted widely as being involved in the modulation of dopaminergic physiology and prefrontal cortex (PFC) function. The COMT Val158Met polymorphism is associated with variation in COMT activity. COMT 158Met allele may be advantageous for PFC-related cognitive abilities; however,...

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Source

Identifiers

PMID: 19700233
DOI: 10.1016/j.bandc.2009.07.011

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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