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Article

Susceptibility to stress in transgenic mice overexpressing TrkC, a model of panic disorder.

Journal of psychiatric research - 1 Feb 2010

Amador-Arjona Alejandro, Delgado-Morales Raúl, Belda Xavier, Gagliano Humberto, Gallego Xavier, Keck Martin E, Armario Antonio, Dierssen Mara

Abstract excerpt

Stressful life events increase the susceptibility for subsequent onset of psychiatric disorders in humans. Previous research has implicated neurotrophins in the onset of some stress-related diseases, such as major depression disorder, post-traumatic stress disorder or panic disorder. We have tested the hypothesis that the neurotrophin-3 (NT-3)/TrkC system is a genetic interface mediating the deleterious effects...

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Source

Identifiers

PMID: 19698958
DOI: 10.1016/j.jpsychires.2009.07.008

Genes

CRH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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