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Article

Pharmacological and null mutation approaches reveal nicotinic receptor diversity.

European journal of pharmacology - 30 Mar 2000

Whiteaker P, Marks M J, Grady S R, Lu Y, Picciotto M R, Changeux J P, Collins A C

Abstract excerpt

We have developed an array of assays for nicotinic acetylcholine receptor binding and function. [125I]alpha-Bungarotoxin-, (-)-[3H]nicotine-, and [3H]epibatidine-binding nicotinic acetylcholine receptors were assayed in mouse brain membranes and sections. Nicotinic acetylcholine receptor function was quantified using synaptosomal [3H]dopamine, [3H]gamma-aminobutyric acid ([3H]GABA), and 86Rb(+) efflux techniques....

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Identifiers

PMID: 10771005
DOI: 10.1016/s0014-2999(00)00052-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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