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Article

C. elegans PAT-4/ILK functions as an adaptor protein within integrin adhesion complexes.

Current biology : CB - 14 May 2002

Mackinnon A Craig, Qadota Hiroshi, Norman Kenneth R, Moerman Donald G, Williams Benjamin D

Abstract excerpt

BACKGROUND: Mammalian integrin-linked kinase (ILK) was identified in a yeast two-hybrid screen for proteins binding the integrin beta(1) subunit cytoplasmic domain. ILK has been implicated in integrin-mediated signaling and is also an adaptor within integrin-associated cytoskeletal complexes. RESULTS: We identified the C. elegans pat-4 gene in previous genetic screens for mutants unable to assemble...

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Topics

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Share to Cell Adhesion Molecules
Share to Cytoskeleton
Share to Focal Adhesions

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Heparan Sulfate Proteoglycans

Share to Integrins

Share to Macromolecular Substances

Share to Muscles

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Source

Identifiers

PMID: 12015115
DOI: 10.1016/s0960-9822(02)00810-2

Genes

ILK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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