Article
Roles for beta(pat-3) integrins in development and function of Caenorhabditis elegans muscles and gonads.
The Journal of biological chemistry - 28 Sept 2001
Lee M, Cram E J, Shen B, Schwarzbauer J E
Abstract excerpt
Heterodimeric integrin receptors for extracellular matrix (ECM) play vital roles in bidirectional signaling during tissue development, organization, remodeling, and repair. The beta integrin subunit cytoplasmic domain is essential for transmission of many of these signals and overexpression of an unpaired beta tail in cultured cells inhibits endogenous integrins. Unlike vertebrates, which have at least nine beta...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
