Article
MAOA and GYG2 are submitted to X chromosome inactivation in human fibroblasts.
Epigenetics - 16 Aug 2009
Stabellini Raquel, Vasques Luciana R, de Mello Joana Carvalho Moreira, Hernandes Lys Molina, Pereira Lygia V
Abstract excerpt
X chromosome inactivation (XCI) is a comprehensively studied phenomenon that helped to highlight the heritable nature of epigenetic modifications. Although it consists of the transcriptional inactivation of a whole X chromosome in females, some genes escape this process and present bi-allelic expression. Using human fibroblasts with skewed inactivation, we determined allele-specific expression of two X-linked...
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