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Article

Ultra-Deep DNA Methylation Analysis of X-Linked Genes: GLA and AR as Model Genes.

Genes - 4 Jun 2020

De Riso Giulia, Cuomo Mariella, Di Risi Teodolinda, Della Monica Rosa, Buonaiuto Michela, Costabile Davide, Pisani Antonio, Cocozza Sergio, Chiariotti Lorenzo

Abstract excerpt

Recessive X-linked disorders may occasionally evolve in clinical manifestations of variable severity also in female carriers. For some of such diseases, the frequency of the symptoms' appearance during women's life may be particularly relevant. This phenomenon has been largely attributed to the potential skewness of the X-inactivation process leading to variable phenotypes. Nonetheless, in many cases, no...

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Share to alpha-Galactosidase
Share to Chromosomes, Human, X

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CpG Islands

Share to DNA Methylation

Share to Genes, X-Linked

Share to Heterozygote

Share to Receptors, Androgen

Share to X Chromosome Inactivation

Source

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Identifiers

PMID: 32512878
DOI: 10.3390/genes11060620
PMCID: PMC7349208

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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