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Article

DNA methylation assay for X-chromosome inactivation in female human iPS cells.

Stem cell reviews and reports - 1 Nov 2011

Kiedrowski Lesli A, Raca Gordana, Laffin Jennifer J, Nisler Benjamin S, Leonhard Kimberly, McIntire Erik, Mongomery Karen Dyer

Abstract excerpt

Remarkable interest in the epigenetic status of human induced pluripotent stem (iPS) cells inspired numerous studies of their X-inactivation patterns. However, both the presence and the absence of X-inactivation have been described to date in undifferentiated iPS cells. The reasons for the discordant results between different studies are unclear, and further X-inactivation testing is warranted for all female...

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Share to DNA Methylation
Share to DNA Restriction Enzymes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Electrophoresis, Capillary

Share to Induced Pluripotent Stem Cells

Share to Promoter Regions, Genetic

Share to Receptors, Androgen

Share to Repetitive Sequences, Nucleic Acid

Share to X Chromosome Inactivation

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Identifiers

PMID: 21373884
DOI: 10.1007/s12015-011-9238-6

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