Article
Genomic DNA methylation in HLA-Cw*0602 carriers and non-carriers of psoriasis.
Journal of dermatological science - 1 Jul 2020
Tang Lili, Yao Tianyu, Fang Miaohong, Zheng Xiaodong, Chen Gang, Li Mengqing, Wang Dan, Li Xinyu, Ma Haining, Wang Xiangru, Qian Yunhong, Zhou Fusheng
Abstract excerpt
BACKGROUND: HLA-Cw*0602 has long been established as one of the most important genetic biomarkers in psoriasis. However, the epigenetic and gene expression differences between HLA-Cw*0602 carriers and non-carriers has not yet been investigated. OBJECTIVE: We aim to explore the whole-genome methylation and gene expression differences between HLA-Cw*0602 carriers and non-carriers. METHODS: HLA imputation was...
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