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Article

A genetic risk score combining ten psoriasis risk loci improves disease prediction.

PloS one - 29 Apr 2011

Chen Haoyan, Poon Annie, Yeung Celestine, Helms Cynthia, Pons Jennifer, Bowcock Anne M, Kwok Pui-Yan, Liao Wilson

Abstract excerpt

Psoriasis is a chronic, immune-mediated skin disease affecting 2-3% of Caucasians. Recent genetic association studies have identified multiple psoriasis risk loci; however, most of these loci contribute only modestly to disease risk. In this study, we investigated whether a genetic risk score (GRS) combining multiple loci could improve psoriasis prediction. Two approaches were used: a simple risk alleles count...

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Identifiers

PMID: 21559375
DOI: 10.1371/journal.pone.0019454
PMCID: PMC3084857

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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