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Article

Replication of association between a common variant near melanocortin-4 receptor gene and obesity-related traits in Asian Sikhs.

Obesity (Silver Spring, Md.) - 1 Feb 2010

Been Latonya F, Nath Swapan K, Ralhan Sarju K, Wander Gurpreet S, Mehra Narinder K, Singh Jairup, Mulvihill John J, Sanghera Dharambir K

Abstract excerpt

Recent genome-wide association studies (GWAS) in Asian Indians reported strong associations of variants near melanocortin-4 receptor (MC4R) and MLX interacting protein-like (MLXIPL) genes with insulin resistance and several obesity-related quantitative traits (QTs). Here, we evaluated the association of two variants (rs12970134 and rs4450508) near MC4R and a nonsynonymous (Gln241His) variant (rs3812316) in MLXIPL...

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Topics

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Share to Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
Share to Body Mass Index
Share to Body Weight
Share to India
Share to Insulin Resistance
Share to Quantitative Trait, Heritable
Share to Receptor, Melanocortin, Type 4
Share to Waist Circumference

Source

Identifiers

PMID: 19680233
DOI: 10.1038/oby.2009.254

Genes

MC4R
MLXIPL
MLX
TG

Variants

rs12970134
rs12970134

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Replication of association between a common variant near melanocortin-4 receptor gene and obesity-related traits in Asian Sikhs.PMID 19680233Read ↗

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