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Article

Interactive modeling for ongoing utility of pharmacogenetic diagnostic testing: application for warfarin therapy.

Clinical chemistry - 1 Oct 2009

Linder Mark W, Bon Homme Marjorie, Reynolds Kristen K, Gage Brian F, Eby Charles, Silvestrov Natalia, Valdes Roland

Abstract excerpt

BACKGROUND: The application of pharmacogenetic results requires demonstrable correlations between a test result and an indicated specific course of action. We developed a computational decision-support tool that combines patient-specific genotype and phenotype information to provide strategic dosage guidance. This tool, through estimating quantitative and temporal parameters associated with the metabolism- and...

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Source

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Identifiers

PMID: 19679631
DOI: 10.1373/clinchem.2009.125898
PMCID: PMC3131846

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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