Article
A regulatory science perspective on warfarin therapy: a pharmacogenetic opportunity.
Journal of clinical pharmacology - 1 Feb 2009
Kim Myong-Jin, Huang Shiew-Mei, Meyer Urs A, Rahman Atiqur, Lesko Lawrence J
Abstract excerpt
Warfarin is a challenging drug to accurately dose, both initially and for maintenance, because of its narrow therapeutic range, wide interpatient variability, and long list of factors that can influence dosing. Two million people in the United States are initiated on warfarin therapy annually, an...
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