Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Missense polymorphisms of PTPRJ and PTPN13 genes affect susceptibility to a variety of human cancers.

Journal of cancer research and clinical oncology - 1 Feb 2010

Mita Yuichiro, Yasuda Yukiko, Sakai Akiko, Yamamoto Hiromasa, Toyooka Shinichi, Gunduz Mehmet, Tanabe Shunsuke, Naomoto Yoshio, Ouchida Mamoru, Shimizu Kenji

Abstract excerpt

PURPOSE: We investigated the association between incidence of various cancers and four single nucleotide polymorphisms (SNPs), two each in two protein tyrosine phosphatase (PTP) genes, PTPRJ and PTPN13, by a case-control study conducted in Japan. METHODS: The study samples comprised 819 cancer-free controls and 569 cancer cases including lung, head and neck, colorectal, and esophageal cancers. RESULTS: Compared...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arginine
Share to Esophageal Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glutamine

Share to Head and Neck Neoplasms

Share to Incidence

Share to Isoleucine

Share to Methionine

Share to Proline

Source

Identifiers

PMID: 19672627
DOI: 10.1007/s00432-009-0656-7

Genes

PTPRJ
PTPN13

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Missense polymorphisms of PTPRJ and PTPN13 genes affect susceptibility to a variety of human cancers.PMID 19672627Read ↗

PTPRJ haplotypes and colorectal cancer risk.Semantic proximity Read ↗

The PTPN13 Y2081D (T>G) (rs989902) polymorphism is associated with an increased risk of sporadic colorectal cancer.Semantic proximity Read ↗

Single Nucleotide Polymorphisms in the PTPN1 Gene Are Associated with Susceptibility to Esophageal Squamous Cell Carcinoma: A Case-Control Study in Inner Mongolia, China.Semantic proximity Read ↗

Ptprj is a candidate for the mouse colon-cancer susceptibility locus Scc1 and is frequently deleted in human cancersSemantic proximity Read ↗

Role of PTPRJ genotype in papillary thyroid carcinoma risk.Semantic proximity Read ↗

PTPN23[Thr] variant reduces susceptibility and tumorigenesis in esophageal squamous cell carcinoma through dephosphorylation of EGFR.Semantic proximity Read ↗

High PTPRQ Expression and Its Relationship to Expression of PTPRZ1 and the Presence of KRAS Mutations in Colorectal Cancer Tissues.Semantic proximity Read ↗

Allelic association of the human homologue of the mouse modifier Ptprj with breast cancer.Semantic proximity Read ↗

The Functional Variant in the 3'UTR of PTPRT with the Risk of Esophageal Squamous Cell Carcinoma in a Chinese Population.Semantic proximity Read ↗

Somatic mutations and genetic polymorphisms of the PPP1R3 gene in patients with several types of cancers.Semantic proximity Read ↗

PTPN13 rs989902 and CHEK2 rs738722 are associated with esophageal cancer.Semantic proximity Read ↗

Functional short tandem repeat polymorphism of PTPN11 and susceptibility to hepatocellular carcinoma in Chinese populations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.