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Article

Allelic association of the human homologue of the mouse modifier Ptprj with breast cancer.

Human molecular genetics - 15 Aug 2005

Lesueur Fabienne, Pharoah Paul D, Laing Stewart, Ahmed Shahana, Jordan Clare, Smith Paula L, Luben Robert, Wareham Nicholas J, Easton Douglas F, Dunning Alison M, Ponder Bruce A J

Abstract excerpt

Human homologues of mouse cancer modifier genes may play a role in cancer risk and prognosis. A proportion of the familial risk of common cancers may be attributable to variants in such genes, each contributing to a small effect. The protein tyrosine phosphatase receptor type J (PTPRJ) has been recently identified as being the protein encoded by the Scc1 mouse gene (susceptibility to colon cancer-1). In addition,...

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Source

Identifiers

PMID: 16000320
DOI: 10.1093/hmg/ddi237

Genes

PTPRJ

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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