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Article

High PTPRQ Expression and Its Relationship to Expression of PTPRZ1 and the Presence of KRAS Mutations in Colorectal Cancer Tissues.

Anticancer research - 1 Feb 2016

Laczmanska Izabela, Karpinski Pawel, Gil Justyna, Laczmanski Lukasz, Bebenek Marek, Sasiadek Maria M

Abstract excerpt

BACKGROUND: The risk of sporadic colorectal cancer (CRC) is strongly influenced by Iifestyle, environmental and genetic factors. Protein tyrosine phosphatases belong to a group of enzymes whose role in CRC has not yet been intensively studied. They play an important role in activation/de-activation of many enzymes, influencing cell biology by catalyzing reactions opposing those catalyzed by kinases. Protein...

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Source

Identifiers

PMID: 26851024

Genes

PTPRQ
PTPRZ1
KRAS

Provenance

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High PTPRQ Expression and Its Relationship to Expression of PTPRZ1 and the Presence of KRAS Mutations in Colorectal Cancer Tissues.PMID 26851024Read ↗

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