Article
Polymorphism of IL-1alpha(-889) Gene and Its Association with Aggressive Periodontitis.
Iranian journal of allergy, asthma, and immunology - 1 Jun 2009
Kiani Zahra, Tavakkol-Afshari Jalil, Hojjat Hamed, Arab Hamid Reza, Radvar Mehrdad, Sadeghizadeh Mehrdad, Ebadian Ahmad Reza
Abstract excerpt
Adult periodontitis is a complex multifactorial disease whose etiology is not well defined. The pro-inflammatory and bone resorption properties of Interleukine-1alpha (IL-1alpha) strongly suggest a role for this cytokine in the pathogenesis of periodontal disease. Eighty Iranian adult patients with periodontitis and 80 Iranian controls were investigated in this study.In this study we report that the frequency of...
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