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Article

Interleukin-1beta+3953 allele 2: association with disease status in adult periodontitis.

Journal of clinical periodontology - 1 Oct 1998

Gore E A, Sanders J J, Pandey J P, Palesch Y, Galbraith G M

Abstract excerpt

Adult periodontitis is a complex multifactorial disease whose etiology is not well defined. The pro-inflammatory and bone resorptive properties of interleukin-1 beta (IL-1beta) strongly suggest a role for this cytokine in the pathogenesis of periodontal disease. In the study reported here, the frequency of IL-1beta genotypes including allele 2 of the IL-1beta+3953 restriction fragment length bi-allelic...

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Identifiers

PMID: 9797049
DOI: 10.1111/j.1600-051x.1998.tb02370.x

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